General Cell Based Assays
Eurofins Discoverx PathHunter eXpress IL17RD/TNFR2 Dimerization Assay, 10pl Kit. (93-1068E3CP5L)
The PathHunter IL17RD/TNFR2 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. TNFα) induced dimerization of IL17RD/TNFR2 receptors. This product uses EFC technology. The cell line included overexpresses IL17RD target protein fused to PK alongside TNFR2 target protein fused to EA. Upon ligand-induced dimerization of IL17RD/TNFR2, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress NPSR1b U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0822E3CP0M)
The PathHunter NPSR1b eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. neuropeptide S) based activation of NPSR1b GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged NPSR1b and EA-tagged β-Arrestin-2. Activation of NPSR1b stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter Teriparatide Bioassay Kit, 2-Plate. (95-0118Y2-00057)
The cAMP Hunter Teriparatide Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses Teriparatide based activation of PTHR GPCR activity via detection of levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type PTHR, a naturally Gs coupled GPCR. Upon activation of PTHR, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Bioassay Systems EnzyChrom™ HDL and LDL/VLDL Assay Kit. For quantitative determination of HDL and LDL/VLDL cholesterol and evaluation of drug effects on HDL and LDL/VLDL metabolism.
For quantitative determination of HDL and LDL/VLDL cholesterol and evaluation of drug effects on HDL and LDL/VLDL metabolism. Key Features: Sensitive and accurate. Requires only 20 µL serum sample. Detection limit of 5 mg/dL, linearity up to 300 mg/dL cholesterol in 96-well plate assay. Convenient. Room temperature assay. No 37°C heater is needed. Convenient and high-throughput. Homogeneous "mix-incubate-measure" type assay. Can be readily automated on HTS liquid handling systems for processing thousands of samples per day. Method: OD340nm. Samples: Serum. Species: All. Procedure: Assay takes 60 min. Kit size: 100 tests. Detection limit: 5 mg/dL.
Eurofins Discoverx PathHunter eXpress rPROKR2 CHO-K1 β-Arrestin GPCR Assay, 10pl Kit. (93-0482E2RCP0L)
The PathHunter rPROKR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prokineticin) based activation of rPROKR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rPROKR2 and EA-tagged β-Arrestin-2. Activation of rPROKR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Xanthine/Hypoxanthine Assay Kit
Xanthine/Hypoxanthine Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter Human MLNR β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human MLNR β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure MLNR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Echelon Biosciences Research Labs SHUTTLE PIP KIT PI(3 4 5)P3
Echelon Biosciences - Shuttle PIP Kit - P-9039 - PI(3,4,5)P3 This item is non returnable
Creative Biomart Follitropin
The product is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin which consists of two non-covalently linked non-identical glycoproteins designated as the alpha- and beta- subunits The alpha- and beta- subunits have 92 and 111 amino acids The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24 The product beta is produced in genetically engineered CHO
Eurofins Discoverx PathHunter Human NPBWR2 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human NPBWR2 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure NPBWR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse MIP-3 alpha (CCR6) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Mouse MIP-3 alpha (CCR6) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure mCCR6 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ILEX LIFE SCIENCES LLC QuickZyme Sensitive Tissue Collagen Assay Kit, 5 x 96 Assays Bulk Pack, 96-well plate format, colorimetric assay for low level collagen analysis (tissue, tissue homogenates samples)
QuickZyme Sensitive Tissue Collagen Assay Kit enables collagen analysis in small tissue samples with low collagen levels. The assay is based on quantitative colorimetric determination of hydroxyproline residues, obtained by acid hydrolysis of collagen. The assay allows quantitative measurement of all types of collagen, species independent. The only hydroxyproline-based assay which shows no matrix effect and no need for further dilution of hydrolysate. No drying of hydrolysate is needed, resulting in a fast and easy (96-well plate format) assay. Application: tissues with low collagen/hydroxyproline content (ex. liver). Sensitivity: 2.4 µM (0.3 µg/ml). Assay-time: < 2 hours. Collagen is a main component of extracellular matrix. Dysregulation in collagen production results in pathologies such as fibrosis (too much collagen), or osteoarthritis (too little collagen). Thus measurement of collagen production is important in many disease related studies.
Abcam D-Lactate Assay Kit (Colorimetric).
D-Lactate Assay Kit (Colorimetric).
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter Human Heregulin β1 (EGFR/ErbB3) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human Heregulin β1 (EGFR/ErbB3) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of EGFR/ErbB3. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.